Diprogenta: What It Is, How It Is Used, And Side Effects
The skin is a very important part of our body. But as with the rest of the parts of our body, it is susceptible to various injuries, diseases and infections, making it necessary to resort to medicine to relieve and cure any ailments that may occur.
As we already know, there are a large number of creams and drugs designed to treat dermatological problems. One of them is the diprogenta which we are going to talk about throughout this article.
A powerful drug with numerous effects on human skin is called diprogenta and is used in treatment of various skin diseases It is a substance composed mainly of betamethasone dipropionate and gentamicin sulfate, the first being a type of corticosteroid and the second an aminoglycoside antibiotic with an effect on different bacteria.
These components therefore make diprogenta have anti-inflammatory, bactericidal and vasoconstrictive effects in addition to reducing pruritus or itching, although its use should not exceed two weeks because excessively prolonging treatment with this substance can generate important side effects (especially due to the use of corticosteroids).
It acts relatively quickly and its effects last over time, and can generally be applied once or twice a day. It is a drug that It is sold in cream form whose application must be carried out on healthy skin (never on wounds) and there is no other route of administration other than the skin since it is the route by which it is best metabolized.
It is necessary to be careful to avoid ingesting it, as well as avoiding contact with the eyes. The dosage will have to be indicated by the doctor in each case, although generally it is indicated that a thin layer of this drug be spread.
Indications
Diprogenta is a very useful drug in the treatment of various skin conditions, especially those injuries and inflammations complicated by a secondary infection later.
It is commonly used in dermatoses (generic name for skin diseases), among which its use stands out in cases of dermatitis (whether atopic, solar, seborrheic, contact, poisonous or exfoliative), in eczema, in allergic reactions or in psoriasis, reducing inflammation and calming itching and discomfort as well as treating possible infections sensitive to the action of gentamicin.
Yes, this product It has bactericidal properties, but not antifungal so it will not be effective in diseases generated by fungi such as candidiasis.
Side effects
As we have indicated previously, diprogenta is a powerful drug whose use must be restricted in time and applied in a very limited manner, given that it can give rise to different side effects and even poisoning.
Among the side effects that arise from excessively prolonged use and in very large areas of the body, atrophy and cracking of the skin, dryness or maceration of the skin (weakening and softening of the skin), inflammation of hair follicles, allergic reactions, infections, redness, acne and skin rashes, stretch marks or the appearance of of hair.
Other more serious side effects would include alterations not only in the skin but in other systems and even in the development process in minors (which may delay growth): it can cause suppression of the hypothalamic-pituitary-adrenal axis, hyperglycemia (of great severity especially in diabetic patients), blood and intracranial hypertension, worsening of glaucoma, hyperthyroidism, cholesterol, ulcer, cataracts, blurred vision, alopecia, drop in blood potassium level or even Cushing’s syndrome. It can also affect the kidneys and liver, making prolonged use toxic.
In addition to that, tolerance to gentamicin may also occur which would facilitate subsequent infections resistant to said antibiotic.
Contraindications and precautions
Diprogenta is a very powerful drug that has a large number of side effects if used incorrectly, and there are also a series of contraindications and precautions that must be taken into account before prescribing it.
It is contraindicated in children under twelve years of age, and its use in those who have reached that age should be done with great caution. due to possible disruption of the endocrine system and hormonal since it could have important effects on its development.
It is also contraindicated in the case of pregnant women (especially in the first trimester) and lactating women unless the benefits outweigh the possible risks, given that although there is not enough data in humans in this regard, it has been shown that it can generate alterations in the fetus in rats.
Obviously this product should not be used if you are allergic to its components. It should also not be used for fungal or viral infections in case of tuberculosis or syphilis, in oral, ocular or genital inflammations, in reactions to vaccines or in deep wounds.
Likewise, you should avoid using this product in large areas, its use in areas covered with bandages or in areas of the skin with a large number of folds, and its prolonged use should especially be avoided. Its use in psoriasis, although it may be an indication for diprogenta, must be extremely controlled and carried out under supervision. Finally, it is not recommended to mix it with substances that may interact with it.
