Suxidine: Uses And Side Effects Of This Medication
Gastrointestinal symptoms are some of the most frequent manifestations when we are exposed to excessive nervous tension. To treat these manifestations there are numerous remedies, among which is pharmacology.
Precisely Suxidine is a medication used to treat diseases of the digestive system related to important stressful situations. We will see below the main characteristics of said drug, as well as some recommendations in case of use.
Suxidine is a drug used to treat different symptoms of the digestive system, related to anxiety states. It contains the following chemical compounds: talc, colloidal silica, calcium carbonate, methylene casin, magnesium stearate, dibasic calcium phosphate, casin.
It has mild anxiolytic properties, as a consequence of one of its active ingredients, Oxazepam Hemisuccinate The latter acts quickly and is almost completely absorbed, without food intervening in it. It is a low-toxic chemical compound, which usually remains in the system for 8 hours and is eliminated by the liver.
It also contains metoclopramide hydrochloride, which acts as a regulator of gastrointestinal motility and prevents spasms of the tract This is absorbed through the digestive tract and metabolized by the liver after approximately 4 hours. Metoclopramide has a slightly higher toxicity, capable of causing digestive and nervous disorders, especially in children.
It also contains polyenzym-S, a compound of synthetic digestive enzymes of a protein nature, which when interacting with natural enzymes, promote the digestion process Finally, suxidine contains antifoaming silicone, which serves to reduce intestinal gases without significantly modifying gastric pH.
In Spain, suxidine in tablet presentation was authorized for marketing on February 1, 1974, by SEID, SA laboratories.
This authorization has been revoked as of July 27, 2018, so it is currently not marketed in that country. However, in other countries its distribution may continue, so we will see below some uses and characteristics of this drug.
What is it for and how is this drug taken?
suxidin It usually comes in tablets and with a medical prescription The average dose for adults is 3 to 6 daily. In the case of children, it is contraindicated for children under 11 years of age.
Likewise, this drug is indicated to treat the following clinical manifestations associated with acute stress and anxiety:
1. Neurovegetative dystonia
Also known as dysautonomia. Dystonias are movement disorders that affect muscle contractions. As the term itself indicates, neurovegetative dystonia is a condition of the vegetative nervous system, responsible for regulating involuntary movements, for example those of the digestive system. It is characterized by a acceleration or decrease of the organs that make up said apparatus
2. Nervous dyspepsia
Dyspepsias are motility disorders of the digestive system, specifically affecting the upper gastrointestinal tract. They impair the secretion of said organ and cause pain, swelling and stomach irritation. It is called nervous dyspepsia because has a psychogenic origin
3. Neurosensory-motor dyspepsia
Like the previous one, it is a motility disorder of the digestive system, but, in this case, the origin of the disorder may be linked to the activity of the sensory nervous system and to the activity of the sensory nerves.
Impairment of bile motility, specifically it involves excessive or inappropriate movements of the muscles that regulate bile secretion.
5. Neurogenic gastritis
Also known as nervous gastritis, since its origin is prolonged and intense exposure to stressful situations. Gastritis is characterized by inflammation of the mucosa that lines the stomach and protects it from acidity.
6. Gastroenteritis
It is an inflammation of the internal membrane that lines both the stomach and the intestine, that is, it causes swelling of the intestinal tract, generating diarrhea, vomiting and pain. It is generally caused by the activity of viruses and bacteria
7. Gastroduodenal ulcer
Also known as peptic ulcer, it is a sore located on the inner membrane of the stomach or the first part of the small intestine It occurs due to a rupture of said membrane and can be caused by bacteria or other diseases, such as alcohol consumption, drugs, tobacco or stress.
8. Irritable bowel
Functional digestive disorder that mainly affects the activity of the intestine, generating abdominal pain, constipation, diarrhea and other symptoms.
Contraindications and side effects
Its use should be avoided in people whose gastric motility may worsen while taking this medication. For example, people who have bleeding, obstruction or perforation in any organ of the digestive system. In addition It is contraindicated in people with tardive or neuroleptic dyskinesia (motor disorder related to prolonged intake of some neuroleptic drugs).
Furthermore, it can enhance the antidopaminergic effects in the central nervous system and the sedative effects of many substances, so its combination with phenothiazines, tranquilizers, hypnotics, narcotics and alcohol should be avoided. On the other hand, Its action decreases when it interacts with other active ingredients such as digoxin and cimetidine
It is not recommended to use it during pregnancy and breastfeeding, and it is also recommended to avoid situations that require an active state of alert, due to its sedative effects.
Among the most common side effects is drowsiness, and in elderly people, prolonged use can cause tardive dyskinesia. These last are the effects that can cause an overdose of this medication
Likewise, prolonged treatment can cause breast tension, galactorrhea (milk production outside of period), amenorrhea (absence of menstruation for more than 90 days), gynecomastia (increase in breast size in men), impotence and hyperprolactinemia ( increased prolactin levels in the blood).
As for the most serious reactions, extrapyramidal reactions such as muscle spasms in the face, neck and tongue have been observed in children and adolescents.
