These Areas Of The Brain Cause The Emotional Changes In Bipolar

These areas of the brain cause the emotional changes in Bipolar

Bipolar disorder is a complex mental condition that affects millions of people around the planet. It is characterized by the appearance of extreme changes in mood, which can range between episodes of mania and hypomania and periods of deep depression. These emotional ups and downs not only impact the personal and professional lives of sufferers, but can also interfere with their relationships and overall well-being.

Despite the prevalence of this disorder, questions remain about the brain mechanisms that drive these drastic emotional changes. Recent research has begun to shed light on this topic, identifying specific areas of the brain that play a critical role in regulating emotions and mood.

In this article I will explain to you which brain regions influence the emotional swings of people with bipolar disorder. offering a clearer view of this complex disease.

What is bipolar disorder?

Bipolar disorder is a mental health condition characterized by extreme changes in mood, ranging from episodes of mania or hypomania to periods of depression. During manic phases, people may experience excessive euphoria, increased energy, decreased need for sleep, and impulsive behaviors. In contrast, during depressive phases, they may feel deep sadness, lack of energy, hopelessness, and loss of interest in activities they previously enjoyed.

These emotional changes are not just isolated episodes; They can significantly interfere with daily life, affecting relationships, work performance, and overall quality of life. People with bipolar disorder often face challenges in their ability to manage their emotions, which can lead to cycles of behavior and mood that are difficult to control. Recognizing and understanding this condition is essential to improve the lives of those who suffer from it.

    The role of emotions in bipolar disorder

    Emotions play a crucial role in the lives of people with bipolar disorder, affecting how they perceive and respond to their environment. These individuals often experience drastic mood swings that can influence their decision making and social interactions. When they are in a positive emotional state, they can view situations optimistically, allowing them to enjoy pleasurable experiences and feel motivated. However, in times of emotional low, they may interpret the same situations in a negative way, which contributes to a cycle of hopelessness and demotivation.

    Additionally, emotional changes can be unpredictable, creating uncertainty and anxiety in daily life. This emotional variability not only affects personal well-being, but can also have an impact on interpersonal relationships and job stability. Understanding how emotions influence bipolarity is essential to developing effective management and treatment strategies.

    Recent research focused on areas of the brain

    A recent study published in Biological Psychiatry Global Open Science focuses on identifying areas of the brain associated with emotional changes in people with bipolar disorder. The research included 21 participants diagnosed with this condition and 21 healthy control people, all of whom underwent functional magnetic resonance imaging (fMRI). The goal of the study was to measure brain activity in response to monetary rewards while participants played a gambling video game.

    During the experiment, the times when participants experienced mood swings related to their wins or losses were assessed. The researchers used a mathematical model to calculate the “momentum” of mood, analyzing how they felt based on their results. This approach allowed for a more precise view of how areas of the brain respond to pleasurable experiences and how this relates to emotionally extreme episodes in bipolar disorder.

      Brain areas involved

      The study revealed the involvement of two key areas of the brain in the emotional experience of people with bipolar disorder: the ventral striatum and the anterior insula.

      1. Ventral striatum

      The ventral striatum is an essential part of the reward system, which is activated in response to pleasurable experiences and It is associated with the release of dopamine, a neurotransmitter essential in the regulation of pleasure and motivation. During the game, participants with bipolar disorder showed significantly higher activity in the ventral striatum compared to people in the control group, indicating that they experienced a stronger sense of reward when winning.

      2. Anterior insula

      On the other hand, the anterior insula plays a crucial role in awareness and perception of emotions. The findings showed that, while controls exhibited synchronization in activity between the ventral striatum and the anterior insula, participants with bipolar disorder represented reduced communication between these two areas. This suggests that although individuals with bipolar may experience an increase in feelings of reward, their ability to recognize and regulate their moods in response to these experiences is impaired. This disconnection can contribute to the emotional instability and extreme mood cycles characteristic of the disease.


      • Emily Psychology

        I’m Emily Williams Jones, a psychologist specializing in mental health with a focus on cognitive-behavioral therapy (CBT) and mindfulness. With a Ph.D. in psychology, my career has spanned research, clinical practice and private counseling. I’m dedicated to helping individuals overcome anxiety, depression and trauma by offering a personalized, evidence-based approach that combines the latest research with compassionate care.